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Public Health Analytics & Decision Intelligence

Disease Surveillance & Outbreak Intelligence

Subnational epidemiological analysis for early detection and public-health decision-making.

Simulated data · Fictionalized geographyEpidemiological analysis · Decision support

01 / The question

Can routine data reveal an emerging signal early enough to act?

Look beyond the case count: check the data, locate the unusual increase, and decide what needs investigation first.

02 / The data

A simulated surveillance setting.

This analysis uses a simulated, de-identified surveillance dataset structured to reflect routine subnational disease-surveillance workflows. Geographic and facility identifiers are fictionalized. No patient-identifiable or confidential programme data are included.

Analysis-ready records
696
Epidemiological weeks
26
Diseases analysed
4

All cases, deaths and signals are simulated scenarios, not actual events in a real jurisdiction.

03 / Data quality

Make the evidence usable first.

716raw records preserved
696analysis-ready records
  • 8 duplicate case IDs identified16 affected rows; 8 duplicate copies excluded.
  • 12 implausible agesFlagged and excluded from the core analysis. No imputation.
  • 18 missing lab resultsKept distinct from pending and not-collected results.

20 records excluded in total. Raw records and quality flags remain available in the analytical workflow.

04 / Person, place & time

Burden and severity tell different stories.

Reported disease burden

Eligible cases · Observed case fatality ratio (CFR)

Measles366 cases · 1.1% CFR
Cholera217 cases · 4.6% CFR
Meningitis70 cases · 7.1% CFR
Lassa fever43 cases · 16.3% CFR
Measles has the largest burden; Lassa fever has the highest observed CFR. CFR reflects recorded outcomes, not population risk.

Age distribution

Years · Eligible cases

0–492
5–14129
15–24167
25–34154
35–4491
45–5444
55–6416
65+3
Most records are in ages 15–24 and 25–34. Sex distribution: 358 male, 338 female.

05 / The outbreak signal

A sharp increase at EW16.

EW15 is the first threshold exceedance. EW16 strengthens the signal, with 36 cases and 3 deaths.

Weekly casesRolling signal threshold
Weekly cholera cases and rolling signal threshold, EW1–26Cases exceed the threshold in EW15, EW16 and EW22. EW16 peaks at 36 cases against a threshold of 12.97. All weekly values are available in the expandable table below.EW1: 18 casesEW2: 7 casesEW3: 1 casesEW4: 5 casesEW5: 18 casesEW6: 6 casesEW7: 10 casesEW8: 4 casesEW9: 5 casesEW10: 5 casesEW11: 7 casesEW12: 5 casesEW13: 6 casesEW14: 4 casesEW15: 12 casesEW16: 36 casesEW17: 9 casesEW18: 5 casesEW19: 8 casesEW20: 5 casesEW21: 1 casesEW22: 10 casesEW23: 10 casesEW24: 8 casesEW25: 3 casesEW26: 9 cases
EW15First threshold exceedance
EW1636 cases · 3 deaths
Epidemiological week · Dots mark threshold exceedances. EW1–4 have no threshold because four preceding weeks are required.

EW15

12 cases

0 deaths · Mean 5.50
Threshold 7.74

EW16

36 cases

3 deaths · Mean 6.75
Threshold 12.97

EW22

10 cases

1 deaths · Mean 4.75
Threshold 9.73

Method and all weekly values

The threshold is the preceding four complete weeks’ mean + 2 standard deviations. The current week is excluded. Values below retain the workbook’s reported precision. This transparent portfolio method does not replace disease-specific national thresholds.

The threshold rises after the peak because the rolling baseline incorporates it. Subsequent non-exceedance does not establish that risk has resolved.

Weekly cholera analysis; “—” means unavailable
EWCasesDeathsPrior meanThreshold
1180——
270——
310——
450——
51827.7520.35
6607.7520.35
71007.5020.18
8409.7519.99
9509.5020.22
10516.2510.81
11716.0010.70
12505.257.43
13605.507.24
14405.757.41
151205.507.74
163636.7512.97
179014.5040.02
185015.2539.89
198015.5039.68
205014.5039.50
21116.7510.33
221014.759.73
231016.0012.78
24806.5014.04
25307.2514.65
26907.7513.47

06 / Where should attention go?

Concentrate the investigation.

During EW15–17, Central and East Districts carry the highest operational priority.

Central District

24 cases · 1 death

5.33× immediate baseline

East District

18 cases · 1 death

12.00× immediate baseline

Central carried the larger case burden, while East showed the sharper increase relative to baseline.

Fictional districts. Ratios compare the weekly mean in EW15–17 with EW11–14; they are not population incidence ratios.

07 / So what?

Each finding changes the next action.

Unusual increase
Verify cases
Geographic concentration
Prioritize investigation
Deaths identified
Review severity and case-management readiness
Reporting delays
Strengthen notification
Unresolved laboratory status
Follow specimens and results

08 / Recommended action

Verify. Investigate. Reassess.

  1. Verify

    0–24 hours

    Check cases, onset dates, locations and outcomes; coordinate through the surveillance chain.

  2. Investigate

    24–72 hours

    Assess clustering and common exposures; review case-management readiness.

  3. Lab follow-up

    0–48 hours

    Resolve specimen status and reconcile pending results.

  4. Active case search

    0–48 hours

    Review registers and seek additional cases in priority facilities and communities.

  5. Reassess

    Within 7 days

    Review reporting delays and repeat signal assessment with verified and newly reported cases.

Activities overlap: laboratory follow-up and active case search begin alongside verification and investigation.

09 / Important interpretation

A signal is a reason to investigate.

It does not, by itself, confirm an outbreak, prove transmission or establish a common source.

Interpretation and limitations
  • Case verification, epidemiological linkage, laboratory evidence where applicable and field investigation are needed before stronger conclusions.
  • No district population denominators are available; district-specific incidence cannot be calculated.
  • Incomplete laboratory information and absent exposure/WASH variables limit transmission hypotheses.
  • The operational priority index combines burden, growth, deaths and reporting delay. It is not a validated prediction score.
  • The simulated dataset demonstrates analytical reasoning, not a real surveillance event.

10 / Tools & capabilities

Analysis that supports a decision.

Analytical workflow developed in Excel, from preserved source records to quality assessment, epidemiological interpretation and a proportionate action pathway.

  • Data quality assessment
  • Descriptive epidemiology
  • Person-place-time analysis
  • CFR interpretation
  • Signal detection
  • Reporting-timeliness assessment
  • Operational prioritization
  • Public-health decision support
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